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In the course of medical research data on the time to the occurrence of a partic of a patient are frequently encountered Such data ular event such as the death are generically referred to as survival data However the event of interest need not necessarily be death but could for example be the end of aperiod spent in remission from a disease relief from symptoms or the recurrence of a particular condition Although there are a number of books devoted to the analysis of sur vival data this book is designed to meet the need for an intermediate text which emphasises the application of the methodology to survival data arising from med ical studies which shows how widelyavailable computer software can be used in survival analysis and which will appeal to statisticians engaged in medical re search This book is based on a course on the analysis of survival data from clinical trials which has been given annually by the Statistical Services Centre ofthe Department of Applied Statistics University of Reading since 1986 Although it is written primarily for those working as statisticians in the pharmaceutical industry and in medical research institutes much of the text should be accessible to numerate scientists and clinicians working alongside statisticians on the analysis of their own data sets This book could also be used as a text to accompany undergraduate and postgraduate courses on survival analysis in universities and other institutes of higher education
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Reduce your risk of costly litigation Written in easytounderstand language by a team of medical doctors who are also attorneys at law this handbook addresses the issues surrounding the growing incidence of medical malpractice It examines the scenarios that can result in a malpractice suit the best actions to take during the course of litigation and the most effective ways to minimize your legal liabilitiesAccess the expert guidance of top professionals across medical and legal fields in an easytoread format Review the legal aspects of nearly every medical topic that impacts health care professionalsQuickly see how to minimize your legal liabilities with the aid of Golden Rule boxesUnderstand the different types of malpractice suits and the physicians position and defense in eachSee how concepts apply to specific scenarios through abundant case studiesExplore specific legal considerations for each medical specialty
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Modelling Survival Data in Medical Research describes the modelling approach to the analysis of survival data using a wide range of examples from biomedical research Well known for its nontechnical style this third edition contains new chapters on frailty models and their applications competing risks nonproportional hazards and dependent censoring It also describes techniques for modelling the occurrence of multiple events and event history analysis Earlier chapters are now expanded to include new material on a number of topics including measures of predictive ability and flexible parametric models Many new data sets and examples are included to illustrate how these techniques are used in modelling survival data Bibliographic notes and suggestions for further reading are provided at the end of each chapter Additional data sets to obtain a fuller appreciation of the methodology or to be used as student exercises are provided in the appendix All data sets used in this book are also available in electronic format online This book is an invaluable resource for statisticians in the pharmaceutical industry professionals in medical research institutes scientists and clinicians who are analyzing their own data and students taking undergraduate or postgraduate courses in survival analysis
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Critically acclaimed and resoundingly popular in its first edition Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advancesparticularly in softwaremade in the field over the last 10 years Now more than ever it provides an outstanding text for upperlevel and graduate courses in survival analysis biostatistics and timetoevent analysisThe treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data including the Cox regression model the Weibull proportional hazards model and others This edition features a more detailed treatment of topics such as parametric models accelerated failure time models and analysis of intervalcensored data The author also focuses the software section on the use of SAS summarising the methods used by the software to generate its output and examining that output in detail Profusely illustrated with examples and written in the authors trademark easytofollow style Modelling Survival Data in Medical Research Second Edition is a thorough practical guide to survival analysis that reflects current statistical practices
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